Signal transduction and the gasotransmitters : NO, CO, and H2S in biology and medicine

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
The Evolution of Gasotransmitter Biology and Medicine....Pages 3-31
Interactions Between Gasotransmitters....Pages 33-55
Front Matter....Pages 57-57
Nitric Oxide....Pages 59-94
Chemical Interaction of Nitric Oxide With Protein Thiols....Pages 95-107
Nitric Oxide and Adenosine Triphosphate-Sensitive Potassium Channels....Pages 109-122
Interaction of Nitric Oxide and Related Radical Species With K Ca Channels....Pages 123-136
Nitric Oxide and Voltage-Gated Ca 2+ Channels....Pages 137-155
Interactions of Nitric Oxide and Cardiac Ion Channels....Pages 157-168
 S -Nitrosylation of Cyclic Nucleotide-Gated Channels....Pages 169-183
Front Matter....Pages 185-185
Synthesis and Metabolism of Carbon Monoxide....Pages 187-203
Interaction of Carbon Monoxide With K + Channels in Vascular Smooth Muscle Cells....Pages 205-218
Modulation of Multiple Types of Ion Channels by Carbon Monoxide in Nonvascular Tissues and Cells....Pages 219-230
The Molecular Mechanisms Underlying the Effects of Carbon Monoxide on Calcium-Activated K + Channels....Pages 231-247
Carbon Monoxide and Signal Transduction Pathways....Pages 249-258
Carbon Monoxide-Induced Alterations in the Expression of K Ca Channels in Pulmonary Artery Smooth Muscle Cells....Pages 259-272
Front Matter....Pages 273-273
Hydrogen Sulfide Production and Metabolism in Mammalian Tissues....Pages 275-292
Toxicological and Environmental Impacts of Hydrogen Sulfide....Pages 293-313
Hydrogen Sulfide and the Regulation of Neuronal Activities....Pages 315-321
The Role of Hydrogen Sulfide as an Endogenous Vasorelaxant Factor....Pages 323-332
Hydrogen Sulfide and Visceral Smooth Muscle Contractility....Pages 333-344
Front Matter....Pages 273-273
Interaction of Hydrogen Sulfide and Adenosine Triphosphate-Sensitive Potassium Channels in Vascular Smooth Muscle Cells....Pages 345-355
Front Matter....Pages 357-357
Gasotransmitters as a Novel Class of Metabolic Regulators....Pages 359-369
Back Matter....Pages 371-377