Targeted therapies in cancer : with 25 tables

Front Matter....Pages I-XIV
Front Matter....Pages 1-1
Beyond Typing and Grading: Target Analysis in Individualized Therapy as a New Challenge for Tumour Pathology....Pages 3-6
Oncogenic Signaling Pathways and Deregulated Target Genes....Pages 7-24
Predictive Pathology of Cytostatic Drug Resistance and New Anti-cancer Targets....Pages 25-32
Prediction of Response to Neoadjuvant Chemotherapy in Carcinomas of the Upper Gastrointestinal Tract....Pages 33-36
Resistance-Associated Signatures in Breast Cancer....Pages 37-50
Resistance to Chemotherapy in Ovarian Carcinoma....Pages 51-60
Clinical, Biological, and Molecular Aspects of Metastasis in Colorectal Cancer....Pages 61-80
Prediction of Efficacy and Side Effects of Chemotherapy in Colorectal Cancer....Pages 81-88
Proteomic Expression Profiling of Breast Cancer....Pages 89-120
Front Matter....Pages 121-121
Targeted Therapy and Blood-Brain Barrier....Pages 123-133
Cetuximab: Appraisal of a Novel Drug Against Colorectal Cancer....Pages 135-143
C-kit, GIST, and Imatinib....Pages 145-151
Antibody Therapy in Non-Hodgkin’s Lymphoma: The Role of Rituximab, 90Y-Ibritumomab Tiuxetan, and Alemtuzumab....Pages 153-163
Molecular and Clinical Aspects of Proteasome Inhibition in the Treatment of Cancer....Pages 165-176
Individualized Target Therapy of Malignant Lymphomas: An Outlook....Pages 177-188
Antiangiogenesis, Anti-VEGF(R) and Outlook....Pages 189-199
Morphological Detection of Hormone and Growth Factor Receptors in Breast Cancer....Pages 201-209
Front Matter....Pages 211-211
Antigen-Specific Cancer Vaccines....Pages 213-218
Therapeutic Vaccination for the Treatment of Malignant Melanoma....Pages 219-227
Monoclonal and Recombinant Antibodies with T Cell Receptor-Like Reactivity....Pages 229-241
Front Matter....Pages 211-211
New Molecular Therapy Targets in Acute Myeloid Leukemia....Pages 243-262