Tumor Suppressor Genes

00 preface_ Tumor Suppressor Genes......Page 1
01 Tumor Suppressor Gene
p16/INK4A/CDKN2A and Its Role
in Cell Cycle Exit, Differentiation,
and Determination of Cell Fate......Page 13
02 Susceptibility of Epithelium to
PTEN-Deficient Tumorigenesis......Page 47
03 Identification of Tumor Suppressor Genes via
Cell Fusion and Chromosomal Transfer......Page 65
04 TP53 Gene Polymorphisms in Cancer Risk:
The Modulating Effect of Ageing, Ethnicity
and TP53 Somatic Abnormalities......Page 91
05 Epigenetics and Tumor Suppressor Genes......Page 123
06 Therapeutic Targeting of p53-Mediated
Apoptosis Pathway in Head and
Neck Squamous Cell Carcinomas:
Current Progress and Challenges......Page 141
07 Signaling Mechanisms of Transforming
Growth Factor-β (TGF-β) in Cancer:
TGF-β Induces Apoptosis in Lung Cells
by a Smad-Dependent Mechanism......Page 157
08 Refining the role of Lgl, Dlg and Scrib
in Tumor Suppression and Beyond:
Learning from the Old Time Classics......Page 193
09 Epigenetic and Posttranscriptional Alterations
of Tumor Suppressor Genes in Sporadic
Pituitary Adenomas......Page 233
10 Genomic and Expression Alterations of
Tumor Suppressor Genes in Meningioma
Development, Progression and Recurrence......Page 259
11 Control of Retinal Development
by Tumor Suppressor Genes......Page 281
12Properties of Human Tumor Suppressor
101F6 Protein as a Cytochrome b561 and
Its Preliminary Crystallization Trials......Page 307
13 Epigenetic Control of Tumor Suppressor
Genes in Lung Cancer......Page 321