Multiple sclerosis : national clinical guideline for diagnosis and management in primary and secondary care

Contents......Page 5
Preface......Page 9
Executive Summary......Page 11
Glossary......Page 15
1 Introduction......Page 24
2 Methodology......Page 30
3 General principles of care......Page 37
4 Disease diagnosis and specific treatment......Page 58
5 Rehabilitation and maintenance: functional activities and social participation......Page 92
6 Diagnosis and treatment of specific impairments......Page 105
7 Monitoring quality: audit and governance......Page 151
8 Research questions......Page 155
Appendices......Page 160
Appendix A: Expanded model of illness......Page 161
Appendix B: Issues for people with MS and their carers......Page 162
Appendix C: Literature searches......Page 166
Appendix D: Searching for health economics evidence......Page 169
Appendix E: Health economics of comparing different methods of administration of methylprednisolone in the treatment of acute......Page 171
Appendix F: Economic evidence for nuclear magnetic resonance imaging scans in the diagnosis of MS......Page 176
Appendix G: The McDonald Criteria......Page 179
Appendix H: Assessments and measures......Page 183
Appendix I: Evidence tables......Page 187
Appendix J: The scope of the clinical guideline......Page 188
References......Page 191