Immunobiology of Proteins and Peptides V: Vaccines Mechanisms, Design, and Applications

Front Matter....Pages i-xi
Developments toward a Recombinant Pertussis Vaccine....Pages 1-7
Prospects and Problems in Synthetic Vaccine Development: What did We Learn from the Cholera Toxin System?....Pages 9-16
New Concepts in Vaccines for Mucosal Non-Enteric Human Bacterial Pathogens....Pages 17-31
Stable Recombinant Avirulent Salmonella Vaccine Strains....Pages 33-47
Cytotoxic and Helper T-Lymphocyte Responses to Antibody Recognition Regions on Influenza Virus Hemagglutinin....Pages 49-63
Haemophilus b Oligosaccharide-CRM 197 and Other Haemophilus b Conjugate Vaccines: A Status Report....Pages 65-82
The Application of Molecular Biology to the Development of Novel Vaccines....Pages 83-98
Studies on the Clonality of the Antibody Response to a Protein Epitope....Pages 99-112
Anti-Idiotype Tumor Vaccines....Pages 113-127
A VH Region Synthetic Peptide Induces Antibodies Which Bind Native Immunoglobulins and Augment an Immune Response to Antigen....Pages 129-143
Enhancement of Primary and Secondary Immune Responses by Interferon-Gamma....Pages 145-152
Interleukin 1 and Its Synthetic Peptides as Adjuvants for Poorly Immunogenic Vaccines....Pages 153-160
Protection Induced by Synthetic Peptides Corresponding to Three Serotypes in Foot and Mouth Disease Virus....Pages 161-167
Characterization of a Synthetic Envelope Peptide of SRV-1 and SRV-2 Virus That Specifically Binds Rhesus Anti-SRV-1 and Anti-SRV-2 Neutralizing Antibodies....Pages 169-173
Synthetic Peptide Representing a T-Cell Epitope of CRM197 Substitutes as Carrier Molecule in a Haemophilus Influenzae Type B (HIB) Conjugate Vaccine....Pages 175-180
The Use of Mouse Class II MHC Peptides to Produce Site-Specific Monoclonal Antibodies....Pages 181-185
Epitope Mimicry by Anti-Idiotype Sequences in Reverse Orientation....Pages 187-190
Vaccine-Containing Biodegradable Microspheres Specifically Enter the Gut-Associated Lymphoid Tissue Following Oral Administration and Induce a Disseminated Mucosal Immune Response....Pages 191-202
Potentiation of Cell-Mediated Immune Responses Directed against P. Falciparum Sporozoite Peptide Vaccine by Immunomodulators....Pages 203-207
Detoxification of Pertussis Toxin by Site-Directed Mutagenesis....Pages 209-214
Filamentous Fusion Phage Cloning Vectors for the Study of Epitopes and Design of Vaccines....Pages 215-218
Recombinant-Derived Modified-Live Herpesvirus Vaccines....Pages 219-236
Advances in Understanding Structure-Function Relationships in Hepatitis B Virus (HBV) Envelope (ENV) Proteins....Pages 237-250
Antigenic Variation during Persistent Lentivirus Infections and Its Simplications for Vaccine Development....Pages 251-272
Antigenic Structure of the Fusion Glycoprotein of Respiratory Syncytial Virus....Pages 273-278
SIV Infected Rhesus Macaques: An AIDS Model for Immunoprevention and Immunotherapy....Pages 279-293
The Development of Molecular Vaccines against Malaria Sporozoites....Pages 295-313
Developing a Gonococcal Protein I Vaccine....Pages 315-327
The Genetics of the Immune Response to Trichinella spiralis Antigens in the Mouse....Pages 329-340
Modulation of Antibody Responses by Conjugates of Antigens with Monomethoxypolyethylene Glycol....Pages 341-351
Back Matter....Pages 353-356