Magnetic Particle Imaging: A Novel SPIO Nanoparticle Imaging Technique

Front Matter....Pages 1-14
Front Matter....Pages 1-1
Characterization of Resovist® Nanoparticles for Magnetic Particle Imaging....Pages 3-7
Nonlinear Behavior of Magnetic Fluid in Brownian Relaxation: Numerical Simulation and Derivation of Empirical Model....Pages 9-13
Magnetic Particle Imaging Using Ferromagnetic Magnetization....Pages 15-20
Magnetic Particle Imaging: Exploring Particle Mobility....Pages 21-25
System Calibration Unit for Magnetic Particle Imaging: Focus Field Based System Function....Pages 27-31
Front Matter....Pages 33-33
Characterization of Magnetic Nanoparticles for Magnetic Particle Imaging by Magnetorelaxometry, AC Susceptibility, Magnetic Particle Spectroscopy and Static Magnetization Measurements....Pages 35-40
Perspectives of Magnetic Particle Spectroscopy for Magnetic Nanoparticle Characterization....Pages 41-45
Initial MPS Response of Adsorptively-Coated Fluorescent Iron Oxide Nanoparticles....Pages 47-52
Evaluation of Different Magnetic Particle Systems with Respect to Its MPI Performance....Pages 53-57
Determination of System Functions for Magnetic Particle Imaging....Pages 59-64
Front Matter....Pages 65-65
Microfluidic System as a Tool for Magnetic Separation of Human Cells with Diagnostic Relevance....Pages 67-71
Potential of Improving MPI Performance by Magnetic Separation....Pages 73-78
Front Matter....Pages 79-79
Fractionated Magnetic Multicore Nanoparticles for Magnetic Particle Imaging....Pages 81-85
Precision Synthesis of Iron Oxide Nanoparticles and Their Use as Contrast Agents....Pages 87-91
Synthesis of Single-Core Iron Oxide Nanoparticles as a Tracer for Magnetic Particle Imaging....Pages 93-97
New Perspectives for MPI: A Toolbox for Tracer Research....Pages 99-103
Superparamagnetic Iron Oxide Nanoparticles: Evaluation of Stability of SPIONs in Different Milieu for Magnetic Particle Imaging....Pages 105-109
3D Semi-quantification of Nanoparticle Content in Tissue on Experimental and Commercial μ CT-Scanner....Pages 111-115
Biomaterials for Regenerative Medicine: Cytotoxicity of Superparamagnetic Iron Oxide Nanoparticles in Stem Cells....Pages 117-122
Tracer Development for Magnetic Particle Imaging....Pages 123-127
Front Matter....Pages 79-79
The Potential of Magnetic Particle Imaging in the Competitive Environment of Cardiac Diagnostics....Pages 129-134
Iron Oxide Nanoparticles – Tracer for Magnetic Particle Imaging....Pages 135-139
Front Matter....Pages 141-141
Experimental Evaluation of Correlation-Based Image Reconstruction Method for Magnetic Particle Imaging....Pages 143-148
Relaxation in x-space Magnetic Particle Imaging....Pages 149-153
Linear and Shift Invariance of Magnetic Particle Imaging....Pages 155-160
Efficient Positioning of the Field-Free Point in Magnetic Particle Imaging....Pages 161-165
Visualization of Instruments in interventional Magnetic Particle Imaging (iMPI): A Simulation Study on SPIO Labelings....Pages 167-172
Front Matter....Pages 173-173
Red Blood Cells as Magnetic Carriers for MPI Applications....Pages 175-179
Ex Vivo Magnetic Sentinel Lymph Node Detection in Colorectal Cancer with a SPIO Tracer....Pages 181-185
Distribution of Superparamagnetic Nanoparticles in Lymphatic Tissue for Sentinel Lymph Node Detection in Breast Cancer by Magnetic Particle Imaging....Pages 187-191
Behavior of Superparamagnetic Iron Oxides in Magnetic Targeting Models....Pages 193-197
Diagnostic Imaging in Cancer Therapy with Magnetic Nanoparticles....Pages 199-203
Engineering Contrast Agents for Gastrointestinal Magnetic Particle Imaging: The Biological Perspective....Pages 205-210
Visualization of Instruments for Cardiovascular Intervention Using MPI....Pages 211-215
Efficient Encoding Methods for Small Numbers of Pixels to Achieve High Sensitivity for Screening....Pages 217-221
Front Matter....Pages 223-223
Influence of Magnetic Field Optimization on Image Quality Achieved for Efficient Radon-Based Reconstruction in Field Free Line Imaging in MPI....Pages 225-229
Slicing Frequency Mixed Traveling Wave for 3D Magnetic Particle Imaging....Pages 231-235
Magnetic-Particle-Imaging for Sentinel Lymph Node Biopsy in Breast Cancer....Pages 237-241
Experimental 3D X-Space Magnetic Particle Imaging Using Projection Reconstruction....Pages 243-247
Enlarging the Field of View in Magnetic Particle Imaging – A Comparison....Pages 249-253
Front Matter....Pages 223-223
Continuous Focus Field Variation for Extending the Imaging Range in 3D MPI....Pages 255-259
Third Generation X-Space MPI Mouse and Rat Scanner....Pages 261-265
Projection X-Space MPI Mouse Scanner....Pages 267-271
Front Matter....Pages 273-273
Reconstruction of Magnetization Curve Using Magnetic Spectroscopy....Pages 275-279
Multiferroic behavior of BTO-Nanoparticles....Pages 281-285
Point Spread Function Analysis of Magnetic Particles....Pages 287-292
Front Matter....Pages 293-293
Spatially Resolved Measurement of Magnetic Nanoparticles Using Inhomogeneous Excitation Fields in the Linear Susceptibility Range (<1mT)....Pages 295-300
Magnetorelaxometry for In-Vivo Quantification of Magnetic Nanoparticle Distributions after Magnetic Drug Targeting in a Rabbit Carcinoma Model....Pages 301-305
Front Matter....Pages 307-307
A Control Unit for a Magnetic Particle Spectrometer....Pages 309-312
Optimization of Circular Current Distributions for Magnetic Field Generation in MPI: A Comparison of the Selection Field Coil and the Drive Field Coil Geometry....Pages 313-318
Capacitor Distortion in Magnetic Particle Imaging....Pages 319-324
Safety Limits for Human-Size Magnetic Particle Imaging Systems....Pages 325-330
Mouse Bed Optimized for MPI....Pages 331-335
Transmembrane Voltages Caused by Magnetic Fields – Numerical Study of Schematic Cell Models....Pages 337-342
Concept for a Modular Class-D Amplifier for MPI Drive Field Coils....Pages 343-347
A Hybrid Filter Topology for a Reduction of High Frequency Harmonics....Pages 349-354
Safety Aspects for a Pre-clinical Magnetic Particle Imaging Scanner....Pages 355-359
Front Matter....Pages 361-361
Citrate-Coated Magnetite Nanoparticles Are Highly Efficient Agents for Magnetic Labeling of Human Mesenchymal Stem Cells....Pages 363-364
Dendronized Iron Oxides as Smart Nano-objects for Multimodal Imaging....Pages 365-366
Superparamagnetic Dextran Coated Iron Oxide Nanoparticles (SPIO) as Potential Markers for Tumor Cell Detection....Pages 367-368
Front Matter....Pages 361-361
Low Field NMR as a Tool for Neuronal Current Detection: A Feasibility Study in a Phantom....Pages 369-370
Low Field Nuclear Magnetic Relaxation of Water and Brain Tissue....Pages 371-371
 In Vivo Biodistribution and Pharmacokinetics of Optimized Magnetic Particle Imaging Tracers....Pages 373-373
Imaging with Optimized Magnetite MPI Tracers....Pages 375-375
A Magnetometer Cooled with Liquid Nitrogen for the Characterization and Quantification of Magnetic Nanoparticles in Biological Samples at Room Temperature....Pages 377-378
Uniform Magnetite Nanoparticles Larger Than 20 nm Synthesized by an Aqueous Route....Pages 379-379
Back Matter....Pages 0--1